Research Article | Open Access

Haematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats

    Emmanuel Chinedu Onuoha

    Department of Haematology/Transfusion Science, Faculty of Medical Laboratory Science, Federal University, Otuoke, Bayelsa State, Nigeria

    Ezekiel Fayiah Hallie

    School of Pharmacy, University of Liberia, Monrovia, Liberia

    Chima Ikoro

    Department of Obstetrics and Gynaecology, Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria


Received
30 Sep, 2024
Accepted
29 Oct, 2024
Published
30 Oct, 2024

Background and Objective: Coconut water has been traditionally recognized for its numerous health benefits, particularly for hydration and its rich nutrient profile. However, its impact on hematological parameters has not been extensively studied. This study aims to investigate Hematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats. Materials and Methods: The 24 Wistar rats were divided into control and treatment groups, with the latter receiving 10, 20 and 30 mL/kg body weight of Malayan green dwarf hybridized immature coconut water. Hematological parameters, including hematocrit, hemoglobin concentration, RBC count, mean cell volume (MCV), mean cell haemoglobin (MCH) and mean cell haemoglobin concentration (MCHC), were assessed. Results: The administration of coconut water resulted in significantly higher hematocrit (p = 0.001), hemoglobin (p = 0.002) and RBC counts (p = 0.006) in the treatment groups compared to the control. However, no significant changes were observed in MCV, MCH or MCHC (p>0.05). Additionally, there was no dose-dependent effect on the hematological parameters among the different treatment groups. Malayan green dwarf hybridized immature coconut water significantly improves hematocrit, hemoglobin and RBC counts in Wistar rats without affecting red cell indices. Conclusion: The effects are consistent across different dosages, indicating its potential as a natural supplement for improving hematological health.

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APA-7 Style
Onuoha, E.C., Hallie, E.F., Ikoro, C. (2024). Haematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats. Pharmacologia, 15(1), 23-28. https://doi.org/10.3923/pharmacologia.2024.23.28

ACS Style
Onuoha, E.C.; Hallie, E.F.; Ikoro, C. Haematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats. Pharmacologia 2024, 15, 23-28. https://doi.org/10.3923/pharmacologia.2024.23.28

AMA Style
Onuoha EC, Hallie EF, Ikoro C. Haematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats. Pharmacologia. 2024; 15(1): 23-28. https://doi.org/10.3923/pharmacologia.2024.23.28

Chicago/Turabian Style
Onuoha, Emmanuel, Chinedu, Ezekiel Fayiah Hallie, and Chima Ikoro. 2024. "Haematological Assessment of Tender Coconut Water as a Natural Erythropoietic Agent in Wistar Rats" Pharmacologia 15, no. 1: 23-28. https://doi.org/10.3923/pharmacologia.2024.23.28