Significant Anaesthetic Effects of Butorphanol

A typical technique for thoracic diagnosis and treatment is fibreoptic bronchoscopy. The senior population uses it frequently. However, disagreeable problems are more common among the elderly than among the younger population. For fibreoptic bronchoscopy, dexmedetomidine and midazolam are most frequently used in clinical settings. Propofol has similar safety to that of midazolam but outperforms it in reducing recovery time, which is crucial for older patients. It can be applied to a variety of endoscopies without building up inside the body. Common opioids with potent analgesic properties include butorphanol and sufentanil. This study's main goal is to serve as a guide for choosing the best anaesthesia techniques.

As study participants, 180 elderly individuals with diagnoses received painless ultrasonic bronchoscopy in the hospital. A random number table was used to divide them into three groups, each with 60 cases: Group I (propofol group), Group II (sufentanil and propofol group), and Group III (butorphanol and propofol group). All the patients were denied food for six hours and water for four hours before the procedure. An 18 G indwelling needle in the vein of the upper limb was used to create venous access as soon as the patient entered the operation room. Each group's propofol dosage, bronchoscopy time, anaesthesia onset and recovery times were recorded, and the effectiveness of the anaesthetic was assessed. When under anaesthesia, there were more adverse responses and problems in each group. SPSS 19.0 software was used for statistical analysis.

HR measures the heart's capacity to compensate for variations in volume, metabolism, stress response, and cardiac function (normal value: 60-100 beats minG-1). When the incidence of adverse responses was examined amongst the three groups, it was discovered that Group I had a respiratory incidence rate that was substantially greater (21.67%) than Groups II (1.67%) and III (0%) (p 0.05). Fibreoptic bronchoscopy's intense stimulation of the respiratory system tends to harm the patient's psychology and spirit and instil anxiety in them. The analgesic impact of butorphanol is 4–8 times greater than that of morphine, yet it has just a fifth of the effects on breathing. To assess its clinical utility, butorphanol and propofol were utilized in ultrasonic bronchoscopy in this investigation.

The BIS is a measure of the cerebral cortex's functional condition. It can efficiently track patients' levels of consciousness and anaesthesia depth during general anaesthesia, enabling precise assessment of the level of anaesthesia. BIS was therefore used in this study to gauge the degree of anaesthesia. The findings indicated that the anaesthesia levels in all three groups were within the normal range, indicating that the anaesthesia techniques used in each group were both secure and efficient. With an incidence rate of roughly 30%, nausea and vomiting are frequent side effects following surgical anaesthesia. Butorphanol did not induce vomiting or central excitement like sufentanil did.

In conclusion, butorphanol and propofol combined for induction can reduce the length of the bronchoscopy and recovery time, increase patient comfort, and produce better anaesthesia, analgesia, and sedation effects as well as fewer postoperative adverse reactions, making it more appropriate for ultrasonic bronchoscopy.

JOURNAL REFERENCE

Guo, X., H. Li, H. Zhang, J. Su and M. Hu et al., 2022. Significant anesthetic effects of butorphanol combined with propofol on ultrasonic bronchoscopy for the elderly. Int. J. Pharmacol., 18: 562-569.